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Because Zocor may damage the liver, your doctor may order a blood test to check your liver enzyme levels before you start taking the drug. Blood tests will probably be done before your treatment is started and at periodic intervals for a year after your final dosage increase. If your liver enzyme levels rise too high, your doctor may tell you to stop taking Zocor.

Since Zocor may cause damage to muscle tissue, be sure to tell your doctor of any unexplained muscle tenderness, weakness, or pain right away, especially if you also have a fever or feel sick. Your doctor may want to do a blood test to check for signs of muscle damage.

If you are scheduled for major surgery, your doctor will have you stop taking Zocor a few days before the operation.

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